<< Home << Products
Column chromatography silica gel
Column chromatography silica gel
.jpg "Column chromatography silica gel")
Column Chromatography Silica Gel Description
Column Chromatography Silica Gel is one of the highly acclaimed techniques for separation as well as analysis of various complex organic mixtures. We are the major manufacturers of Column Chromatography Silica Gel. To meet the different needs of the clients, we offer Column Chromatography Silica Gel in various particle sizes for pilot plant or other plant applications.
All chromatographic methods -with the exception of TLC- use columns for the separation process. Column chrom-atography has found its place in many laboratories for preparative purposes as well as for reaction control in organic syntheses. The importance of column chromatography is mainly due to following factors:
Simple packing procedure
Low operating pressure
Low expense for instrumentation
Column chromatography is separated into two categories, depending on how the solvent flows down the column. If the solvent is allowed to flow down the column by gravity, or percolation, it is called gravity column chromatography. If the solvent is forced down the column by positive air pressure, it is called flash chromatography, a "state of the art" method currently used in organic chemistry research laboratories.
The Adsorbent
Silica gel (SiO2) and alumina (Al2O3) are two adsorbents commonly used by the organic chemist for column chromatography. These adsorbents are sold in different mesh sizes, as indicated by a number on the bottle label: “silica gel 60” or “silica gel 230-400” is a couple examples. This number refers to the mesh of the sieve used to size the silica, specifically, the number of holes in the mesh or sieve through which the crude silica particle mixture is passed in the manufacturing process.
Adsorbent particle size affects how the solvent flows through the column. Smaller particles (higher mesh values) are used for flash chromatography; larger particles (lower mesh values) are used for gravity chromatography. For example, 70–230 silica gels are used for gravity columns and 230–400 mesh for flash columns.
Grades Available
35-70 mesh
60-120 mesh
70-230 mesh
100-200 mesh
200-400 mesh
230-400 mesh
400-800 mesh
Features and Benefits
High resolution
Batch to Batch reproducible results
Excellent flow rates
Direct scalability
Typical Data of Silica gel Column Grade Adsorbents
Iron Content - < 0.02%
Chloride Content - < 0.10%
Loss on Drying - <3%
pH (10% suspension) - 7 ± 0.5
Surface Area - 400–600 m2/gm
Column Chromatography Silica Gel is one of the highly acclaimed techniques for separation as well as analysis of various complex organic mixtures. We are the major manufacturers of Column Chromatography Silica Gel. To meet the different needs of the clients, we offer Column Chromatography Silica Gel in various particle sizes for pilot plant or other plant applications.
All chromatographic methods -with the exception of TLC- use columns for the separation process. Column chrom-atography has found its place in many laboratories for preparative purposes as well as for reaction control in organic syntheses. The importance of column chromatography is mainly due to following factors:
Simple packing procedure Low operating pressure Low expense for instrumentation Column chromatography is separated into two categories, depending on how the solvent flows down the column. If the solvent is allowed to flow down the column by gravity, or percolation, it is called gravity column chromatography. If the solvent is forced down the column by positive air pressure, it is called flash chromatography, a "state of the art" method currently used in organic chemistry research laboratories.
The Adsorbent
Silica gel (SiO2) and alumina (Al2O3) are two adsorbents commonly used by the organic chemist for column chromatography. These adsorbents are sold in different mesh sizes, as indicated by a number on the bottle label: “silica gel 60” or “silica gel 230-400” is a couple examples. This number refers to the mesh of the sieve used to size the silica, specifically, the number of holes in the mesh or sieve through which the crude silica particle mixture is passed in the manufacturing process.
Adsorbent particle size affects how the solvent flows through the column. Smaller particles (higher mesh values) are used for flash chromatography; larger particles (lower mesh values) are used for gravity chromatography. For example, 70–230 silica gels are used for gravity columns and 230–400 mesh for flash columns.
Grades Available
35-70 mesh 60-120 mesh 70-230 mesh 100-200 mesh 200-400 mesh 230-400 mesh 400-800 meshFeatures and Benefits
High resolution Batch to Batch reproducible results Excellent flow rates Direct scalabilityTypical Data of Silica gel Column Grade Adsorbents
Iron Content - < 0.02% Chloride Content - < 0.10% Loss on Drying - <3% pH (10% suspension) - 7 ± 0.5 Surface Area - 400–600 m2/gm