Product Name: Silica Gel for Column Chromatography
Chemical Name: Silicon Dioxide, Amorphous
Synonyms: Silicic acid, silicon dioxide
CAS Number: 112926-00-8
Recommended Use: Laboratory sorbent for chromatography applications
Manufacturer: Provided upon request
Emergency Contact Number: Provided upon request
GHS Classification: Not classified as hazardous under GHS
Health Hazards: Not expected to cause acute toxicity, but chronic inhalation may affect lung function. Dust can irritate eyes, skin, and respiratory tract.
Signal Word: None
Hazard Statements: Prolonged exposure to dust forms may lead to respiratory irritation and possible effects on lung health.
Precautionary Statements: Avoid breathing dust. Use only with adequate ventilation. Wear dust mask for prolonged operations.
Physical Hazards: No significant explosive or flammable hazards
Other Hazards: Contains no crystalline silica above regulatory limits
Chemical Composition: Amorphous silicon dioxide
Purity: ≥99% SiO2
Impurities: Trace metal oxides below safety thresholds
Additives: No additional substances present in concentrations classified as hazardous
Form: Granular or powdered solid
Eye Contact: Rinse immediately with plenty of water for several minutes; seek medical advice if irritation develops or persists.
Skin Contact: Wash affected area with soap and water; remove contaminated clothing.
Inhalation: Remove to fresh air. Seek medical attention if symptoms such as shortness of breath or coughing persist.
Ingestion: Rinse mouth and drink water. If discomfort occurs, consult a physician.
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide for surrounding fires.
Unsuitable Extinguishing Media: No limitations identified
Special Hazards: Product is not combustible; may produce irritating dust under fire conditions.
Protective Equipment for Firefighters: Full protective clothing and self-contained breathing apparatus
Specific Methods: Prevent run-off to sewers and waterways; control dust generation.
Personal Precautions: Wear adequate respiratory protection and protective gloves. Avoid dust formation.
Environmental Precautions: Prevent spillage from entering drains or waterways.
Methods for Clean Up: Collect with mechanical means, dampen to control dust, and place in suitable container for disposal.
Emergency Procedures: Restrict access to area and ventilate if necessary until dust dissipates.
Safe Handling Practices: Minimize dust generation and accumulation. Use local exhaust ventilation.
Storage Requirements: Store in tightly sealed containers in cool, dry, well-ventilated areas.
Incompatibilities: Avoid strong acids and hydrofluoric acid.
Hygiene Measures: Wash hands thoroughly after handling. Do not eat, drink, or smoke in work area.
Engineering Measures: Use protective equipment and follow workplace procedures.
Exposure Limits: OSHA PEL (respirable dust): 6 mg/m³; ACGIH TLV (inhalable): 10 mg/m³
Engineering Controls: Use appropriate dust control systems and local exhaust ventilation.
Personal Protective Equipment: Safety glasses, laboratory coats, gloves, and properly fitted particulate respirators for prolonged exposure.
Environmental Controls: Avoid release to the environment—collect waste promptly.
Work Practice Controls: Maintain proper housekeeping and prevent dust accumulation.
Appearance: White to off-white, fine granular or powder
Odor: Odorless
Odor Threshold: Not applicable
pH (suspension): 4.0 – 8.0
Melting Point / Freezing Point: >1600°C
Boiling Point: Not applicable
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Non-flammable
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: ~2.2 g/cm³
Solubility: Insoluble in water and organic solvents
Partition Coefficient: Not available
Auto-Ignition Temperature: Not applicable
Decomposition Temperature: >1600°C
Viscosity: Not applicable
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Moisture, dust formation, strong acids, hydrofluoric acid
Incompatible Materials: Hydrofluoric acid causes hazardous silicon tetrafluoride gas
Hazardous Decomposition Products: None under normal use.
Hazardous Polymerization: Will not occur
Acute Toxicity: No acute toxicity reported under normal laboratory use
Skin Corrosion/Irritation: May cause mild skin irritation on prolonged contact
Serious Eye Damage/Irritation: Dust can irritate eyes
Respiratory Sensitization: Prolonged or repeated exposure to dust can impact lung health
Germ Cell Mutagenicity: No evidence found
Carcinogenicity: Not classified as carcinogenic by IARC or NTP
Reproductive Toxicity: No evidence of reproductive harm
Specific Target Organ Toxicity: Prolonged inhalation may affect the lungs (pneumoconiosis)
Other Information: No signs of systemic toxicity from oral or dermal routes in animal studies
Ecotoxicity: Not expected to be hazardous to aquatic life
Persistence and Degradability: Inorganic compound not biodegradable; remains stable in environment
Bioaccumulative Potential: No bioaccumulation expected due to inert, insoluble nature
Mobility in Soil: Not mobile, due to low solubility
Other Adverse Effects: Large releases may affect habitats physically due to siltation effects
Disposal Methods: Collect product and contaminated packaging for disposal at permitted landfill or incineration facilities, according to local, regional, national, and international regulations.
Contaminated Packaging: Rinse containers before recycling or disposal as per local guidelines.
Special Precautions: Avoid discharge into drains or natural water bodies.
UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: Not considered a marine pollutant
Special Precautions for User: Handle containers with care to avoid spillage and formation of dust during transport.
US Regulations: TSCA listed. No specific OSHA hazards.
EU Regulations: Complies with REACH Regulation (EC) No 1907/2006. Not classified as hazardous.
Canadian Regulations: DSL/NDSL listed.
Other International Regulations: No further restrictions identified.
Product Labeling: Proper hazard communication labeling recommended for workplace containers.
